What is Non-Alcoholic Steatohepatitis?
Non-Alcoholic Steatohepatitis (NASH) is a type of liver disease that affects millions of people worldwide. It is caused by the accumulation of fat in the liver, which can lead to inflammation and scarring. NASH is often associated with obesity, diabetes, and high blood pressure, and can progress to cirrhosis and liver failure if left untreated.
What is Metformin?
Metformin is a medication that is commonly used to treat type 2 diabetes. It works by reducing the amount of glucose produced by the liver and increasing the body’s sensitivity to insulin. Metformin has also been shown to have beneficial effects on the liver, including reducing inflammation and improving liver function.
How Metformin May Help Treat NASH
Recent studies have suggested that metformin may be a potential treatment for NASH. One study found that metformin was able to reduce liver inflammation and improve liver function in patients with NASH. Another study found that metformin was able to reduce the amount of fat in the liver and improve liver function in patients with NASH.
Are There Any Side Effects of Metformin?
Metformin is generally well-tolerated, but it can cause side effects such as diarrhea, nausea, and abdominal pain. It is also important to note that metformin can cause lactic acidosis, a potentially life-threatening condition, in people with certain medical conditions such as kidney disease or heart failure.
Conclusion
While more research is needed to fully understand the potential benefits and risks of metformin as a treatment for NASH, the preliminary evidence suggests that it may be a promising option for patients with this condition. However, it is important to discuss the potential benefits and risks of metformin with a healthcare provider before starting any new medication.